Scientists find a ‘kill switch’ in the body that can destroy cancer cells

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In the fight against cancer, every breakthrough brings hope to millions people affected by this devastating disease.

Now, the scientists at the UC Davis Comprehensive Cancer Center in Sacramento, California presented a new promising route to treatment of cancer. Namely, they detailed the results of their study in a publication of the Cell Death & Differentiation journal.

The findings show that CD95 receptors, known as Fas, or “death receptors,” send a signal that causes cancer cells to “self-destruct.”

“Previous efforts to target this receptor have been unsuccessful. But now that we’ve identified this epitope (target), there could be a therapeutic path forward to target Fas in tumors,” Jogender Tushir-Singh, a senior author of the study and associate professor in the Department of Medical Microbiology and Immunology, stated in the release.

These CD95 receptors are located on the cell surface. Upon activation, they trigger a series of molecular processes that result in cell destruction. They play a crucial role in maintaining a cellular balance but scientists hadn’t explored their full potential until recently.

One of the biggest challenges in the fight against cancer is the therapeutic resistance, meaning the cells develop resistance to conventional treatments.

At the time being, the conventional treatments include surgery, chemotherapy, and radiotherapy.

Additionally, immune-based therapies have been also used in the fight against this disease, such as CAR (chimeric antigen receptor) T-cell therapy, but their effectiveness is limited to only certain types of cancer.

“Despite being decently successful in liquid tumors, such as leukemia spectrum cancers, long-term remission remains the biggest challenge for CAR T-cell therapies,” Tushir-Singh shared with Fox News.

The study revealed that there are now hopes “and potential solution to transform the meager success of CAR-T therapies into potentially successful [therapies for] solid tumors,” not only in treating leukemia.

The discovery of the Fas epitope could eliminate cell evasion by triggering programmed cell death. So, targeting Fas in cancer therapy will not only help overcome therapeutic resistance, but also show potential for enhancing the effectiveness of current immunotherapies.

“It is evident that the success of CAR-T therapy relies on off-target killing by Fas,” Tushir-Singh told Fox News Digital.

Further, he added: “With the current information, we researchers and doctors should screen potential cancer patients — who would be undergoing CAR-T therapy — to check for the comprehensive presence of Fas on their tumors.”

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Teenager vaping the equivalent of 50 cigarettes a day receives shocking diagnosis after coughing up ‘pints’ of blood

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Monica Pop

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Wanting to fit in with his group of friends, Jayden Richardson, now 17, started vaping at the age of just 12. His vaping was excessive, as he’s been consuming the equivalent of 50 cigarettes a day.

His habit took its toll after he started coughing up ‘pints’ of blood on the last day of his holiday in Turkey, where he was together with his family.

Once they returned home, Jayden was immediately rushed to the hospital.

Considering the symptoms, doctors assumed he was suffering from a stomach ulcer, his mother, Elita, said.

She believed the her son developed the condition due to his eating habits, particularly the greasy food and the kebabs he had every day while on holiday. But she couldn’t be more wrong.

After undergoing endoscopy, doctors determined the blood he was coughing was a result of severe lung damage due to his habit of vaping.

Doctors advised him to never use e-cigarettes again, and Jayden was more than determined to break the bad habit. But the promise he had given to himself was only kept until his birthday in January when he reached to the vape yet again.

Sadly, this was a very “stupid” thing to do as the symptoms returned.

At the time being, Jayden is awaiting a CT scan. He hopes that the ban of disposable vapes in June 2025 would add to his efforts to never vape again.

Jayden shared his story, saying, “I was terrified. I never thought vaping could cause all this.

“It started off in Turkey. The night before I had a bit of chest pain but didn’t really think much of it whatsoever. I woke up the next morning, had a quick go on my vape and just as if I had a bit of a chesty cough.

Jayden added: “I went to cough a few times and it felt a bit phlegmy so I went to spit it out. I saw that it was blood and this put me in shock. I didn’t know what to do myself.”

He alerted his mom, who was having breakfast at the time, but once she got to him, it wasn’t really bad.

Later, he went to the pool and had a drink. All of a sudden, he started coughing blood again.

“If I could go back to that moment when I first started [vaping] I’d tell myself ‘never to touch one of them’,” the teen explained. “It’s crazy how dangerous they are and what they can actually do to the human body. You don’t realise it when you do it. It just affects you in the long run. I would never touch one.”

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5-year-old boy dies during treatment after hyperbaric chamber explodes

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Monica Pop

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A five-year-old Michigan boy died in a bizarre, tragic incident during receiving treatment when the hyperbaric chamber exploded.

The tragedy happened at The Oxford Center in Troy, Michigan, on January 31, somewhere before 8 a.m. local time.

The law firm representing the family has identified the victim as Thomas Cooper.

When officers and firefighters arrived at the center, they found young Thomas inside the chamber dead.

Lt. Keith Young of the Detroit Fire Department said the hyperbaric chamber contained 100% oxygen, making it extremely flammable.

“Upon arrival, the first responding units unfortunately discovered a 5-year-old boy deceased on the scene,” Lt. Ben Hancock of the Troy Police Department said at a press conference.

At the time of the explosion, Thomas’ mother was standing near the hyperbaric chamber. She sustained injuries to her arm.

At the time being, an investigation regarding the reasons that led the hyperbaric chamber to explode is ongoing.

James Harrington, managing partner of Fieger Law, the law firm representing the family, released a statement regarding the tragedy, calling it unimaginable.

“We ask that the public and media respect the family’s privacy at this time. We are investigating every aspect of this matter and will report our findings in due time. The safety of children should always be the top priority, and this incident raises serious concerns about hyperbaric chambers and the oversight and regulation of hyperbaric treatments,” the statement read.

A GoFundMe page started to help Thomas’ family said “His family loved him very much.”

Annie Cooper, who organized the fundraiser said, “He was a smart, intelligent boy and his parents loved him how he was. He was perfect in every way. He was the best, best boy there ever was.

Further, Annie said, “He asked to see pictures of germs, liked to know how things worked, he liked to make field journals and he had finally started adding facial features to his people drawings.”

According to his family, “Thomas loved life.”

At the moment, it is still not known what caused the explosion or what kind of treatment the boy was getting.

The website of The Oxford Center, however, states it provides therapy for children with autism, cancer, ADHD, autoimmune diseases, and multiple others.

Our thoughts and prayers go to the grieving family.

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Flight data shows the American Airlines pilots made a desperate attempt to prevent the crash and save all on board

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Monica Pop

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The pilots flying the American Airlines Flight 5342 that collided mid-air with a US Army Black Hawk helicopter on January 29, made a heroic attempt to save everyone on board, new data shows.

The jet carried 64 passengers, and the helicopter was carrying three soldiers who retraining the president’s emergency evacuation route, which is a part of a contingency plan for the continuity of government.

At the time of the accident, the plane was approaching Ronald Reagan Washington National Airport in an attempt to land.

Unfortunately, there are no survivors.

Rescue teams have not recovered all of the bodies up to this point.

Data from the plane’s black box revealed that the pilots, 34-year-old Campos, and his 28-year-old co-pilot Lilley, made a desperate final attempt to pull the plane up seconds before the crash.

“At one point very close to the impact, there was a slight change in pitch, an increase in pitch,” Todd Inman, an official of the National Transportation Safety Board (NTSB), said during a press conference on February 1.

Further, Inman said that they don’t have the data from the helicopter, but “obviously an impact occurred, and I would say when an impact occurs, that is typically where the altitude of both aircraft were at the moment.”

Preliminary data from the plane’s black box showed conflicting readings about the altitudes of both aircraft.

When hit over the Potomac River, the American Airlines plane was flying at an altitude of 325 feet, with a 25ft margin of error on either side.

On the other hand, data provided by the control tower showed that the Black Hawk was flying at an altitude of about 200ft, which is he maximum of what a helicopter can safely operate at in the area.

Hopefully, they would be able to reconcile the differences in the altitude once they get to the data of the helicopter’s black box which was retrieved but waterlogged.

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I Never Expected Such a Harsh Outcome

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Bryan Seal

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I was completely floored when I first read about this Man who burned his thumb loses both legs story. Seriously—how does a minor cooking mishap spiral into something so devastating? Max Armstrong, 40, was just out in the woods of Kiowa, Colorado, enjoying a camping trip. Next thing he knew, a week later, he woke up from a coma with no legs.

A Simple Burn Becomes a Major Crisis

Max said it all started when he grabbed a hot skillet the wrong way while making pasta. He felt the searing pain but shrugged it off—just another scrape or burn from an active, outdoor life. He treated the burn, then went back to camping. A few days later, though, one leg began swelling. He brushed that off too, thinking maybe he’d twisted an ankle at some point. Turns out, the infection creeping through his thumb was way more serious than he imagined.

Shocking Discoveries at the Hospital

By December 7, his toenails turned purple, and the swelling got much worse. At the hospital, doctors were stunned to see the blackened burn on his thumb—it had become severely infected with strep. Before anyone fully realized what was going on, it led to strep sepsis. Max ended up in a coma for six days. When he finally woke on December 13, doctors told his loved ones he might not make it. It was a near-fatal ordeal.

Man Who Burned His Thumb Loses Both Legs in Surgery

The moment Max realized both of his feet had turned completely black was heartbreaking. He learned they had to amputate both legs on December 23 to save his life, because the infection had already spread too far. He spent a month in the hospital, then another 16 days in rehab. Now, he’s leaning on a wheelchair and focusing on exercises that build arm and shoulder strength—he calls them his “lifeline.” Unfortunately, this man who burned his thumb loses both legs in such a bizarre, tragic twist of fate.

On the Road to Recovery

Max says the emotional toll is just as intense as the physical one. He woke up expecting his legs to be there, only to realize they were gone. Yet, he’s determined to bounce back. Friends and family have rallied behind him, even setting up a GoFundMe to help with medical costs. It’s a stark reminder that life can change in an instant—even when you think you’re dealing with a minor injury.

For anyone wanting to support Max’s recovery, click here.

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I’m Still Reeling From This New Hollywood Bombshell

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Bryan Seal

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I honestly did a double take when I saw the headline: Musk Shocks Hollywood by dropping alleged evidence tying Sean “Diddy” Combs to some of the biggest movers and shakers in entertainment. It’s not every day you see such bold claims—especially from a tech mogul more known for rockets than red carpets. But here we are, sifting through a whirlwind of leaked photos and whispered rumors that might just reveal how deep Diddy’s connections really go.

Surprising Snapshots and Silent Celebs

What really threw me were these so-called “leaked” pictures making the rounds online. Apparently, they show Diddy hanging out in private settings with A-list stars. Some folks say it’s nothing unusual—celebrities mingle, end of story. But the chatter around these snapshots suggests something more. Could there be hush-hush partnerships or behind-the-scenes alliances that no one wanted us to see? You can bet fans are dissecting every pixel. So far, many of the celebs rumored to appear haven’t said a peep, which only stirs the pot. No wonder Musk Shocks Hollywood in such a big way.

The Curiosity Behind Musk’s Move

Of course, there’s also the question of why Elon Musk decided to pull back the curtain on this scene. He’s known for stirring up drama—sometimes in business, sometimes in politics. Now he’s shining a spotlight on star-studded secrets? Maybe he’s just intrigued by the “hidden layers” of fame. Or he could be testing the boundaries of what fans and insiders will tolerate. Whatever the reason, one thing’s certain: Musk Shocks Hollywood at a time when many people thought they’d seen it all.

Tinseltown’s Next Chapter

Personally, I’m bracing myself for more fallout. If these leaks spark real tension among the elite, we could see some unexpected alliances crumble—or brand-new feuds ignite. Social media is on fire with theories and finger-pointing, and it’s only been a few days since the story first broke. Will Diddy break his silence? Will other stars be forced to come clean about their ties? All I know is that Musk Shocks Hollywood might become the headline for weeks to come, and I’m totally here for it.

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The black box and flight recorder from the crashed DC helicopter and plane provide crucial altitude data that may help explain the incident

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Monica Pop

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The crash between the American Airlines plane and the US Army Black Hawk helicopter is one of the deadliest US air collisions in recent years. Sadly, all of the people onboard the jet and the helicopter presumed dead.

The jet carried 64 people while the Black Hawk had three members of the military onboard at the time of the tragedy.

Daily Mail reports that the National Transportation Safety Board revealed that flight data recorder and black box from the DC aircraft crash contain altitude readings that could shed light on the cause of the accident.

The American Airlines Flight 5342 was cruising at about 325ft, with a 25ft margin of error on either side. Data from the control tower showed that the Black Hawk was flying at an altitude of about 200ft.

Petty Officer 1st Class Brandon Giles/U.S. Coast Guard/AP

Experts have yet to explain the approximate 100-foot difference in altitude readings. However, if the crash happened at the altitude the plane was reported to be at, the collision happened at an altitude above the maximum of what a helicopter can safely operate at in the area.

At the time being, investigators are trying to retrieve data from the helicopter’s black box, which became waterlogged after submerging into icy waters of the Potomac River.

Hopefully, they would be able to reconcile the differences in the altitude.

Speaking of the ongoing investigation, Brice Banning, NTSB investigator in charge, said, “This is a complex investigation. There are a lot of pieces here. Our team is working hard to gather this data.”

Further, he added the jet’s black boxes revealed the crew having a verbal reaction. As the plane started to increase its pitch, “sounds of impact were audible about one second later, followed by the end of the recording,” Banning added.

President Trump gave his insight into the collision. He said that the helicopter was flying “too high,” and “far above its 200 foot limit.” He added: “That’s not really too complicated to understand, is it???”

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Names of mother and 11-year-old daughter who were on a medical jet that crashed revealed

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Monica Pop

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On January 30, a medical jet flying from the Sates to Mexico, crashed over Philadelphia, killing all six people onboard.

The jet was carrying a mother, and her daughter who received a life-saving surgery at the Shriners Children’s Hospital Philadelphia. Further, a doctor, and a paramedic. There were also two pilots onboard the jet.

Before the tragic accident, the plane reached around 1,500 feet in the air.

Philadelphia Mayor, Cherelle Parker, said in a statement, as per BBC News: “A devastating plane crash occurred in Northeast Philadelphia near Roosevelt Mall at Cottman and Bustleton Avenues on Friday evening, January 31, 2025, at approximately 6:10 pm.

“A private Learjet 55 – a medical transportation jet – departing from Northeast Philadelphia Airport with two passengers, a mother and daughter, and four crew members were killed in the tragic crash.”

Additionally, Shai Gold, a spokesman for Jet Rescue Air Ambulance, which operated the flight, confirmed the tragic news.

He said the young passenger bravely battled an illness.

Officials released the identities of the mother and daughter killed in the crash. They were identified as Lizeth Murillo Ozuna, age 31, and Valentina Guzman Murillo, age 11.

The rest of the people who lost their lives were identified as Dr. Raul Meza Arredondo, paramedic Rodrigo Lopez Padilla, copilot Josue de Jesus Juarez Juarez, and captain Alan Alejandro Montoya Perales.

“It’s extremely hard and extremely difficult, those that were involved directly in her care were very aware that she was going to be traveling home and there had actually been a sendoff for her today,” the hospital where Valentina was receiving treatment said in a statement.

All of the victims were residents of Mexico.

Unfortunately, when the jet crashed, it formed a huge fireball that engulfed several houses and vehicles, claiming the life of a person driving a car at the time of the accident. Their name, however, has not yet been revealed.

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The findings show that CD95 receptors, known as Fas, or “death receptors,” send a signal that causes cancer cells to “self-destruct.”

At the time being, the conventional treatments include surgery, chemotherapy, and radiotherapy.

His habit took its toll after he started coughing up ‘pints’ of blood on the last day of his holiday in Turkey, where he was together with his family.

After undergoing endoscopy, doctors determined the blood he was coughing was a result of severe lung damage due to his habit of vaping.

Later, he went to the pool and had a drink. All of a sudden, he started coughing blood again.

When officers and firefighters arrived at the center, they found young Thomas inside the chamber dead.

At the time being, an investigation regarding the reasons that led the hyperbaric chamber to explode is ongoing.

According to his family, “Thomas loved life.”

Unfortunately, there are no survivors.

Data from the plane’s black box revealed that the pilots, 34-year-old Campos, and his 28-year-old co-pilot Lilley, made a desperate final attempt to pull the plane up seconds before the crash.

Preliminary data from the plane’s black box showed conflicting readings about the altitudes of both aircraft.

A Simple Burn Becomes a Major Crisis

Shocking Discoveries at the Hospital

Man Who Burned His Thumb Loses Both Legs in Surgery

On the Road to Recovery

Surprising Snapshots and Silent Celebs

The Curiosity Behind Musk’s Move

Tinseltown’s Next Chapter

The jet carried 64 people while the Black Hawk had three members of the military onboard at the time of the tragedy.

Hopefully, they would be able to reconcile the differences in the altitude.

Additionally, Shai Gold, a spokesman for Jet Rescue Air Ambulance, which operated the flight, confirmed the tragic news.

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